A new socioeconomic status measure for vaccine research in children using individual housing data: a population-based case-control study

A new socioeconomic status measure for vaccine research in children using individual housing data: a population-based case-control study

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Abstract Background We recently developed HOUSES, an individual housing-based socioeconomic status (SES) measurement for health disparities research.We assessed whether HOUSES was associated with risk of pertussis and pertussis vaccine up-to-date status in children.Methods The study utilized a previous population-based case-control study cohort assembled during the 2004–2005 pertussis outbreak.We collected data on pertussis vaccine status (up-to-date status) at the time of the index date.Using a z-score for housing value, actual square footage, and numbers of bedrooms and bathrooms, HOUSES Shrug was formulated in continuous variable and categorized into quartiles.

Vaccine up-to-date status was compared among subjects with different SES as measured by HOUSES using a chi-square test and logistic regression models.Results Of the 391 eligible pediatric subjects (median age of 13.1 years with male sex of 55 %), 363 (93 %) were successfully geocoded to formulate HOUSES index.HOUSES was not associated with the risk of pertussis (p = 0.82).

Pertussis vaccine up-to-date statuses were 79, 86, 83, and 94 % for children in the first (the lowest SES), second, third, and fourth quartiles of HOUSES, respectively (p = 0.03).HOUSES as a continuous variable was associated Liners with pertussis vaccine up-to-date status (adjusted OR: 1.15 per increment of one unit of HOUSES, 95 % CI: 1.04–1.

27, p = 0.008).Conclusion While HOUSES is not associated with the risk of pertussis, it predicts vaccine up-to-date status among children with different SES.HOUSES may be a useful tool for vaccine delivery research among children.